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北 潔　教授

Professor Kiyoshi KITA

北　潔　教授

     

​担当科目

経歴

所属

  • Basics of Molecular Biology

  • 1972: Graduated from the fuculty of Medicine, University of Tokyo

  • 1974: Master Degree from Graduate School of Medicine, University of Tokyo

  • 1980: PhD. from Graduate School of Medicine, University of Tokyo

School of Tropical Medicine and Global Health (TMGH), Nagasaki University

PhD

研究領域

  • Drug Discovery and Development

専門分野

  • Biochemistry

  • Parasitology

  • Tropical Medicine and Health

その他の関心分野

  • Metabolic Diseases

国/地域

  • Africa

  • Southeast Asia

  • India

  • Central and South America

​メッセージ

　「基礎研究を通して人類の向上と福祉をめざす事」であり、代謝調節と生体膜の生化学および分子生物学などの純粋な基礎生物学的研究とともに、国際的な医療問題に対する共同研究を含めた指導、調査による研究室外の活動を発展途上国から先進国まで積極的に進めている。​

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Selected Publications

1

Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.

Balogun, E.O., Inaoka, D.K., Shiba, T., Kido, Y., Tsuge, C., Nara, T., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P.A.M., Kita, K. & Harada, S. (2014) Mol. Microbiol. 94, 1315-1329

Pharmacophore Modeling for Anti-Chagas Drug Design Using the Fragment Molecular Orbital Method.

Yoshino, R., Yasuo, N., Inaoka , D.K., Hagiwara, Y., Ohno, K., Orita, M., Inoue, M., Shiba, T., Harada, S., Honma, T., Balogun, E.O., da Rocha, J.R., Montanari, C.A., Kita, K. & Sekijima, M. (2015) PLoS One 10, e0125829

In vivo curative and protective potential of orally administered 5-aminolevulinic acid plus ferrous ion against malaria.

Suzuki, S., Hikosaka, K., Balogun, E.O., Komatsuya, K., Niikura, N., Kobayashi, K., Takahashi, K., Tanaka, T., Nakajima, M. & Kita, K. (2015) Antimicrob. Agents Chemother. 59, 6960-6967

Hit and lead criteria in drug discovery for infectious diseases of the developing world.

Katsuno, K., Burrows, J.N., Duncan, K., van Huijsduijnen, R.H., Kaneko, T., Kita, K., Mowbray, C.E., Schmatz, D., Warner, P. & Slingsby, B.T. (2015) Nat. Rev. Drug Discov. 14, 751-758

Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes. 

Goodman, C. D., Siregar, J., Mollard, V., Vega-Rodríguez, J., Safruddin, D., Matsuoka, H., Matsuzaki, M., Toyama, T., Stürm, A., Cozijnsen, A., Jacobs-Loreno, M., Kita, K., Sangkot, M., and McFadden, G. I. (2016) Science, 352, 349-353

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